U.S. Supreme Court Justice Ruth Bader Ginsburg, a worldwide icon for gender equality, has died of metastatic pancreatic cancer at the age of 87, the court confirmed Friday.

Ginsburg was one of the longest-serving Supreme Court Justices, having been appointed to the bench in 1993 by then-President Bill Clinton. She was the second-longest serving woman ever to hold a seat on the country’s highest court.

The justice had recently revealed that her cancer had returned after an earlier battle with the disease.

“Our nation has lost a jurist of historic stature,” Chief Justice John Roberts said in a statement provided by the court. “We at the Supreme Court have lost a cherished colleague."

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